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PICAMILON (aka Nicotinoyl-GABA, Pycamilon, Pikamilon)


PICAMILON (aka Nicotinoyl-GABA, Pycamilon, Pikamilon)

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Picamilon 50mg x 30 pills per bottle. Picamilon (also known as nicotinoyl-GABA, Pycamilon, and Pikamilon) is a dietary supplement formed by combining niacin with GABA. It was developed in the Soviet Union in 1969 and further studied as a prodrug of GABA. The patent rights to the drug belong to pharmaceutical company NPK ECHO ("НПК ЭХО"), Moscow, Russia.

Information below translated from manufacturers Russian language website:

Picamilon dilates blood vessels in the brain. It also has a tranquilizing, psychostimulant, antiplatelet and antioxidant effect. Picamilon improves the functional state of the brain due to normalization of tissue metabolism and the effect on cerebral blood flow (increases the volume and the linear velocity of cerebral blood flow and cerebral vascular resistance decreases, inhibits platelet aggregation, improves microcirculation).

Picamilon Benefits

  • Improves blood flow to the brain

  • Improves physical and mental performance

  • Reduces headaches, relieves migraine attacks

  • Lowers intraocular pressure

  • Improves memory

  • Normalizes sleep

  • Helps reduce or eradicate feelings of anxiety, stress, fear

  • Improves patients with movement and speech disorders, including stroke, and after traumatic brain injury

  • Reduces symptoms of psychomotor disturbances in chronic alcoholism

  • Eases symptoms of alcohol withdrawal and symptoms of "hangover"

  • Normalizes urination

Indications for use:

  • Increase memory efficiency & concentration

  • In the treatment of mild to moderate ischemic cerebrovascular events

  • In chronic cerebrovascular insufficiency

  • After traumatic brain injury

  • In the treatment of chronic alcoholism

  • In the combined therapy for migraine prophylaxis

  • Dystonia (a movement disorder which causes involuntary contractions of your muscles).

  • In the combined therapy of primary open-angle glaucoma with compensated pressure

  • In urological practice (for children aged 3 years and adults with disorders of urination) to improve the adaptive function of the bladder

  • Reduce depression in the elderly & senile psychosis

How to take Picamilon:

Take with or without food but with ample water.

To sharpen memory one 50mg Picamilon tablet 2 times a day as needed.

For cerebrovascular diseases one 50mg Picamilon tablet 2-3 times a day. The course of treatment is 1-2 months. A second course in 5 - 6 months.

For the prevention of migraine attacks - one 50mg Picamilon tablet three times a day. For relief of an attack - two tablets at once.

In depressive states in old age - 2-4 50mg Picamilon tablets 2-3 times daily for 1.5 - 3 months.

To reduce anxiety, with milder forms of depression - 2-3 50mg Picamilon tablets a daily, if necessary up to six tablets per day for 1 - 1.5 months.

In alcoholism during abstinence - 3-4 50mg Picamilon tablets a day for the first week. Thereafter 1-2 tablets daily for 4 - 5 weeks.

Athletic Training; 1-2 50mg Picamilon tablets per day for 1 - 1.5 months.

In primary open-angle glaucoma - One 50mg Picamilon tablet 3 times a day for 1 month.

In disorders of urination - One 50mg Picamilon tablet 3 times a day (for patients older than 15 years). Treatment 1 month. Please note that the effect is most pronounced at the end of the treatment course.


The drug should not be used in hypersensitivity (to Picamilon) or chronic renal failure. Not recommended for pregnant or lactating women.

Possible Side Effects

Picamilon is generally well tolerated. In some cases, allergic reactions (rash, pruritus), dizziness, headache, mild nausea, irritability, anxiety, agitation. The drug can cause flushing - the condition is not dangerous and does not require discontinuation, simply reduce dosage.

Symptoms of Picamilon overdose

Cases of overdose associated with dangerous health effects are unknown. Overdose of Picamilon can increase the severity of side effects. In such cases stop taking the drug. No special treatment is necessary.

Drug Interactions

Picamilon shortens the duration of barbiturates, (phenobarbital for example), and enhances the effects of opioid analgesics (narcotics).


Picamilon shelf life is 3 years. Picamilon should not be used after expiration date printed on the package.

Keep Picamilon stored in a dry, dark place, out of reach of children, at a temperature not exceeding 77° F / 25° C.


Please note the product is manufactured in Russia and the text on the packaging is in Russian.

Note: The FDA has not evaluated or endorsed this product. It is not intended to treat any specific illness or medical condition. Please consult your physician prior to using this or any other nutritional supplements or medications.


Write Review

  1. The real thing

    Posted by David on 6th Dec 2014

    All who have bought "Picamilon' NOT made in Russia -- The difference is considerable . . . this is what Picamilon is supposed to be.

  2. Very good product

    Posted by James on 24th Oct 2014

    PICAMILON very effective when needed . Great service as well .

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